1,3-Dimethylurea N,N’-Dimethylurea

Chemical Property of 1,3-Dimethylurea

● Appearance/Colour: white flake ● Vapor Pressure: 0.00744mmHg at 250 ● Melting Point: 101-104°C(lit.) ● Refractive Index: 1.413 ● Boiling Point: 269 Cat 760 mmHg ● PKA: 14.5710.46(Predicted) ● Flash Point: 124.3°C ● PSA: 41.13000 ● Density: 0.949 g/cm3 ● LogP: 0.32700 ● Storage Temp.: Store at RT. ● Solubility.: H2O: 0.1 g/mL, clear, d ● Water Solubility.: 765 g/L(21.5C) ● XLogP3: -0.5 ● Hydrogen Bond Donor Count: 2 ● Hydrogen Bond Acceptor Count: 1 ● Rotatable Bond Count: 0 ● Exact Mass: 88.063662883 ● Heavy Atom Count: 6 ● Complexity: 46.8

Purity/Quality

99%, *data from raw suppliers N,N"-Dimethylurea *data from reagent suppliers

Safty Information

● Pictogram(s): ● Hazard Codes: ● Statements:62-63-68 ● Safety Statements:22-24/25

MSDS Files

SDS file from LookChem

Useful

● Chemical Classes: Nitrogen Compounds -> Urea Compounds ● Canonical SMILES: CNC(=O)NC ● Inhalation Risk: No indication can be given about the rate at which a harmful concentration of this substance in the air is reached. ● Effects of Short Term Exposure: The substance is mildly irritating to the eyes and skin. ● Description: 1, 3-Dimethylurea is a urea derivative and used as an intermediate in organic synthesis. It is a colorless crystalline powder with little toxicity. It is also used for synthesis of caffeine, pharmachemicals, textile aids, herbicides and other. In the textile processing industry 1,3-dimethylurea is used as intermediate for the production of formaldehyde-free easy-care finishing agents for textiles. In the Swiss Product Register there are 38 products containing 1,3-dimethylurea, among them 17 products intended for consumer use. Product types are e.g. paints and cleaning agents. The content of 1,3-dimethylurea in consumer products is up to 10 % (Swiss Product Register, 2003). Use in cosmetics has been proposed, but there is no information available as to its actual use in such applications.1,3-Dimethylurea is an organic compound with the formula (CH3)2NC(O)NH2. It is a colorless crystalline solid with high solubility in water. 1,3-Dimethylurea is commonly used as a solvent and catalyst in organic synthesis. It can be used in the synthesis of various compounds such as dyes, fluorescent dyes, and plastics. In the pharmaceutical industry, 1,3-dimethylurea is also used to synthesize some pharmaceutical intermediates. In addition, it is used in industries such as coatings and adhesives. It is important to note that 1,3-dimethylurea is irritating to the skin and eyes, so proper safety precautions should be taken when handling. ● Uses: N,N′-Dimethylurea can be used:As a starting material to synthesize N,N′-dimethyl-6-amino uracil. In combination with β-cyclodextrin derivatives, to form low melting mixtures (LMMs), which can be used as solvents for hydroformylation and Tsuji-Trost reactions.To synthesize N,N′-disubstituted-4-aryl-3,4-dihydropyrimidinones via Biginelli condensation under solvent-free conditions.