Synonyms:4(1H)-Pyrimidinone,2,6-diamino- (8CI,9CI);2,4-Diamino-6-hydroxypyrimidine;2,4-Diamino-6-pyrimidinone;2,6-Diamino-3,4-dihydropyrimidin-4-one;2,6-Diamino-4(1H)-pyrimidinone;2,6-Diamino-4(3H)-pyrimidinone;2,6-Diamino-4-hydroxypyrimidine;2,6-Diamino-4-pyrimidinol;2,6-Diaminopyrimidin-4-one;2,6-Diaminopyrimidine-4(3H)-one;6-Aminoisocytosine;6-Hydroxy-2,4-pyrimidinediamine;NSC 44914;NSC 680818;NSC9302;
Chemical Property of 2,4-Diamino-6-hydroxypyrimidine
● Appearance/Colour:white solid
● Vapor Pressure:0.00232mmHg at 25°C
● Melting Point:285-286 °C (dec.)(lit.)
● Refractive Index:1.7990 (estimate)
● Boiling Point:288.5 °C at 760 mmHg
● PKA:10.61±0.50(Predicted)
● Flash Point:128.3 °C
● PSA：98.05000
● Density:1.84 g/cm3
● LogP:0.50900
● Storage Temp.:Desiccate at +4°C
● Sensitive.:Light Sensitive
● Solubility.:DMSO (Slightly), Methanol (Slightly)
Purity/Quality
99% *data from raw suppliers
2,4-Diamino-6-hydroxypyrimidine *data from reagent suppliers
Safty Information
● Pictogram(s):Xi
● Hazard Codes:Xi
● Statements:36/37/38
● Safety Statements:22-24/25-36-26
MSDS Files
SDS file from LookChem
Total 1 MSDS from other Authors
Useful
● Description: 2,4-Diamino-6-hydroxypyrimidine (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesis. In HUVEC cells, the IC50 for inhibition of BH4 biosynthesis is about 0.3 mM. DAHP can be used to effectively block NO production in several cell types.
● Uses: 2,4-Diamino-6-hydroxypyrimidine (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesis. In HUVEC cells, the IC50 for inhibition of BH4 biosynthesis is about 0.3 mM. DAHP can be used to effectively block NO production in several cell types.[Cayman Chemical] It stands at the beginning of the enzyme-catalyzed cascade that starts with this seven-carbon carbohydrate and ends with the aromatic amino acids phenylalanine, tyrosine, and tryptophan 2,4-Diamino-6-hydroxypyrimidine (cas# 56-06-4) is a compound useful in organic synthesis.
2,4-Diamino-6-hydroxypyrimidine is a chemical compound with the molecular formula C4H6N4O. It is commonly used as an intermediate in the synthesis of various compounds, including pharmaceutical drugs and dyes.The compound has a pyrimidine ring structure consisting of two amino groups (NH2) and one hydroxyl group (OH) attached to different carbon atoms. This structure makes it a versatile building block for the synthesis of more complex molecules.2,4-Diamino-6-hydroxypyrimidine can be obtained by various synthetic methods, including the reaction of cyanamide with urea. It has several applications in the pharmaceutical industry, particularly in the synthesis of anticancer drugs and antibiotics.Overall, 2,4-Diamino-6-hydroxypyrimidine is an important compound that finds utility in various chemical and pharmaceutical applications.