Methyl D-(-)-4-hydroxy-phenylglycinate

Synonyms:Benzeneaceticacid, α-amino-4-hydroxy-, methyl ester,(R)-;(R)-Methyl (4-hydroxyphenyl)glycinate;D-(4-Hydroxyphenyl)glycine methylester;D-p-Hydroxyphenylglycine methyl ester;Methyl D-(-)-α-amino-α-(4-hydroxyphenyl)acetate;Methyl (R)-amino(4-hydroxyphenyl)acetate;

Chemical Property of Methyl D-(-)-4-hydroxy-phenylglycinate

● Vapor Pressure:6.03E-05mmHg at 25°C
● Refractive Index:1.57
● Boiling Point:335.7 °C at 760 mmHg
● PKA:9.74±0.26(Predicted)
● Flash Point:156.9 °C
● PSA：72.55000
● Density:1.248 g/cm3
● LogP:1.26530

● Storage Temp.:Room Temperature
● Solubility.:DMSO (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly)
● XLogP3:0.5
● Hydrogen Bond Donor Count:2
● Hydrogen Bond Acceptor Count:4
● Rotatable Bond Count:3
● Exact Mass:181.07389321
● Heavy Atom Count:13
● Complexity:176

Purity/Quality

99% *data from raw suppliers

MethylD-(-)-4-Hydroxy-phenylglycinate *data from reagent suppliers

Safty Information

● Pictogram(s):
● Hazard Codes:

MSDS Files

SDS file from LookChem

Useful

● Canonical SMILES: COC(=O)C(C1=CC=C(C=C1)O)N
● Uses: Methyl D-(-)-4-Hydroxy-phenylglycinate is useful for the synthesis (+)-radicamine B. Also, it is used for the preparation of amoxicillin.
D-4-Hydroxyphenylglycine methyl ester, also known as D-HPG Methyl Ester or D-4-Hydroxyphenylglycine methyl ester hydrochloride, is a chemical compound with the molecular formula C9H11NO3 and the molar mass of 181.19 g/mol. It is the methyl ester form of D-4-Hydroxyphenylglycine.D-4-Hydroxyphenylglycine methyl ester is a chiral compound with a unique structure that includes a phenyl ring and an amino acid backbone. It has been synthesized for various applications, including its use as a building block in organic synthesis and pharmaceutical developments.One significant application of D-4-Hydroxyphenylglycine methyl ester is its involvement in the synthesis of pharmaceuticals. It can serve as a precursor in the production of drugs such as β-lactam antibiotics, peptide analogs, and other bioactive compounds. Its incorporation into the molecule of these drugs can introduce beneficial properties or enhance their activity.Furthermore, D-4-Hydroxyphenylglycine methyl ester shows potential therapeutic properties on its own. It has been studied for its antioxidant, anti-inflammatory, and neuroprotective effects. These properties make it a subject of interest in the development of drugs for various medical conditions, including neurodegenerative diseases.In summary, D-4-Hydroxyphenylglycine methyl ester is a chemical compound with applications in pharmaceutical synthesis and potential therapeutic effects. Its unique structure and chiral nature make it valuable as a building block for drug development, and its demonstrated biological activities suggest its potential for various medical applications.