Synonyms:Uracil
Chemical Property of Uracil
● Appearance/Colour:white powder
● Vapor Pressure:2.27E-08mmHg at 25°C
● Melting Point:>300 °C(lit.)
● Refractive Index:1.501
● Boiling Point:440.5°C at 760 mmHg
● PKA:9.45(at 25℃)
● Flash Point:220.2oC
● PSA：65.72000
● Density:1.322 g/cm3
● LogP:-0.93680
● Storage Temp.:+15C to +30C
● Solubility.:Aqueous Acid (Slightly), DMSO (Slightly, Heated, Sonicated), Methanol (Slightly,
● Water Solubility.:SOLUBLE IN HOT WATER
● XLogP3:-1.1
● Hydrogen Bond Donor Count:2
● Hydrogen Bond Acceptor Count:2
● Rotatable Bond Count:0
● Exact Mass:112.027277375
● Heavy Atom Count:8
● Complexity:161
Purity/Quality
99%, *data from raw suppliers
Uracil *data from reagent suppliers
Safty Information
● Pictogram(s):Xi
● Hazard Codes:Xi
● Safety Statements:22-24/25
MSDS Files
SDS file from LookChem
Total 1 MSDS from other Authors
Useful
● Chemical Classes: Biological Agents -> Nucleic Acids and Derivatives
● Canonical SMILES: C1=CNC(=O)NC1=O
● Recent ClinicalTrials: Study of 0.1% Uracil Topical Cream (UTC) for the Prevention of Hand-Foot Syndrome
● Recent EU Clinical Trials: Onderzoek naar de farmacokinetiek van uracil na orale toediening bij pati?nten met colorectaal carcinoom.
● Recent NIPH Clinical Trials: A phase II trial of uracil ointment for the prevention of capecitabine induced hand-foot syndrome (HFS): .
● Uses: For biochemical research, drugs synthesis; being used as pharmaceutical intermediates, also used in organic synthesis Nitrogenous base on RNA nucleosides. antineoplastic In biochemical research. Uracil (Lamivudine EP Impurity F) is a nitrogenous base on RNA nucleosides.
● Description: Uracil is a pyrimidine base and a fundamental component of RNA where it binds to adenine via hydrogen bonds. It is converted into the nucleoside uridine through the addition of a ribose moiety, then to the nucleotide uridine monophosphate by the addition of a phosphate group.